Large Scale Plasmid DNA Restriction Endonuclease Digest

[weston at skyfox.usask.ca]

I have a large quantity of plasmid (pUC deriviative) DNA to digest
with :
1) EcoRI
2) EcoRI and HindIII double digest.
What is the largest amount of plasmid DNA that anyone has digested at any one
time (one reaction tube)?  I have approximately one milligram of purified
plasmid DNA which needs to be restricted in as short a time as possible.
Thanks in advance.

        Brigitte Weston.