Specificity of antibodies for Conformation

Don Newmeyer donald at LJCRF.EDU
Sat Feb 19 18:08:35 EST 1994

 Joe Kramer <jkramer at ccmail.sunysb.edu> wrote:

>I have injected several proteins(4 or 5) in high urea (4-8M) and obtained
>antibodies which recognized native epitopes.  I haven't found any immun-
>agens which did not work in this regard.
>Joe Kramer

I'm curious: did you really inject the urea solution into the rabbits? I'd expect it to be toxic.

Don Newmeyer
La Jolla Cancer Research Foundation
10901 N. Torrey Pines Rd.
La Jolla, CA  92037

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