cosmid instability

Rosemary Lemons rmlemons at um
Thu Jun 2 07:29:23 EST 1994


We had a library made in the cosmid vector pWe 16 and have also 'heard'
that
it is unstable when grown in culture volumes greater than 1-5 ml.  Our
experience is that this is true.  We, too, would appreciate any further
insight
on how to handle this important yet fragile library.

rmlemons at umich.edu



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