Can a polyclonal AB distinquish between two very similar proteins

Alexander P Rostovtsev rosto001 at
Thu Jun 23 15:51:21 EST 1994

In <2uaoqa$oec at> jaishre at (Jaishree Muppala Chittoor) writes:

>Can a polyclonal AB raised against a synthetic peptide (MNLAPLDT) be able
>to distinguish between a protein with this sequence and a protein that 
>shows >70% sequence identity with it.  This other protein has SNLAPVDT as its 
>sequence at the corresponding region.
>Thanks in advance.
>[jaishre at]

Yes, they can. Polyclonal Abs against Tyr-Gly-Gly recognized [met]- and
[leu]enkepalins and lots of other stuff.


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