Regs for mailing DNA/prions

Robert Preston rapr at MED.PITT.EDU
Thu Jun 23 10:48:09 EST 1994


> In article <Pine.3.87.9406221003.A375-0100000 at chuma>,
> colter at CHUMA.CAS.USF.EDU ("Mary Colter ", BIO) wrote:
> 
> > Does anyone know where I can get REAL information on mailing DNA samples? 
> > This includes info on things such as recombinant DNA, genomic DNA, etc. 
> > if it is considered hazardous (what kinds of disclaimers, etc). The local 
> > post office here is not  really well equipped to deal with these questions.
> > Also Does anyone recognize the word 'prion' or 'pryon' or something that 
> > sounds like this? Is this a company or a product? I have a friend who is 
> > looking for this information. Thanks - replies don't really need to be 
> > posted back to the network,  just e-mail me, please.
> > colter at chuma.cas.usf.edu
> 
> 
> Yes I do reconize the word prion. It is a proteinacous infectious particle
> responible for causing scrapie in sheep and causes Creuzfeld-Jakob (maybe
> misspelled) disease in humans. It is transmitted by cannibalism.  It was
> first thought to be the first form of life that replicates without
> indogenous nucleic acid but somehow it uses that of its host(?). It was
> discovered in the early 80s but I don't know what they have learned since.
> Some investigators have claimed that is does contain DNA but it is so well
> protected by the protein is not easily detected. Who knows.  :)
> 
see also Reed Wickner's article on the [URE3] yeast prion and the associated
reviews in the same issue of Science 264:566 April 22 1994.  Great stories.

Rob 
rapr at med.pitt.edu




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