patent for SDA and LCR
odonnell at sasa.gov.uk
Mon Jun 27 09:59:37 EST 1994
Alex Chang <lpss at unixg.ubc.ca> wrote :
>Anyone knows whether the technique of Stranded Displacement Assay and
>Ligase Chain Reaction have been patented?
>University of British Columbia
>lpss at unixg.ubc.ca
The situation for LCR (Ligase Chain Reaction) is complex, and depends
upon who you ask. The first LCR paper was written by Francis Barany (PNAS
vol.88:189-193). He would certainly seem to be the person who deserves
the credit for developing the technique, and he has an association with
Applied Biosystems, who may be marketing LCR-related products in the
future. However, Abbott Diagnostics also have a stake in LCR and can be
quite stroppy if you phone them up and ask them about it. Their interest
lies in developing automated systems for diagnosis of human pathogens.
Also on the schene are those companies producing LCR-related products,
like Stratgene and New England Biolabs.
How it all fits together, I haven't quite worked out yet. To get to the
nub of your question, I have seen no actual LCR patent and have a
suspicion/hope that the whole question of similar techniques and
precedents is now so tortuous that there will not be one, but that
individual applications (kits) will be patented. The latest I have heard
is a deal between Applied Biosystems and Abbott, whereby AB will provide
Abbott with LCR systems for their kits. What this means for ordinary
researchers I don't know.
Perhaps there is someone out there who is in a better position than me to
continue this story?
Scottish Agricultural Science Agency "We must combine pessimism
East Craigs of the intellect with
Edinburgh Tel. 031 244 8924 optimism of the will."
EH12 8NJ Fax 031 244 8940
Scotland Antonio Gramsci
odonnell at jura.sasa.gov.uk
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