** DEPC and reagents **
ming at ahabs.wisc.edu
Fri Mar 25 16:39:55 EST 1994
In article <9403252029.AA18997 at pines2.ljcrf.edu>, helgew at LJCRF.EDU (Helge
> does anyone know the exact rxn mechanism of DEPC (any approximation
> thereof would be appriciated as well :))?
I am assuming you are talking about diethylpyrocarbonate(DEPC), right?:)
If so, the reaction is a carboxyethlation reaction on N position(if it is a
amino group). The nucleophiles can be others, like His, Cys, tyrosine etc.
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