Protease Inhibitors

schren13 at schren13 at
Wed Mar 30 05:10:45 EST 1994


I am working on a system in which a membrane-bound protein is solubilized by a
membrane protease.

In order to classify the protease, I treated it with various protease
inhibitors. To my surprise I repeatedly get an increased protease activity when
the serine-protease inhibitor "3,4-dichloroisocoumarin" is used. Is there
anyone out there who has an explanation?

Please send any replies by e-mail to rscholle at Thanks a lot.

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