How to Calculate Oligo MW?

Stephen R. Lasky, Ph.D. alt Stephen_Lasky at
Mon Nov 7 09:05:19 EST 1994

In article <N.L.Brown.1134506748B at>, N.L.Brown at
(Nigel Brown) wrote:

> In Article <1994Nov3.140526.1 at>,
> books at wrote:
> >We are looking for a formula to calculate the exact MW for oligonucleotides.
> >The oligo will have a 5'-hydroxy group. We can estimate oligonucleotide MW
> >if we use 330 as the average MW for each base but we need a exact number. 
> >Thanks DPSMITH smith_dennis_p at
> GOOD GRIEF!  I have no objection to helping people with technical and other
> problems of a specialist nature, but are there really people doing science
> who cannot calculate a molecular weight?  No wonder
> bionet.molbio.methds-reagnts is becoming overloaded.

As I suspected, you have started getting people flaming you (gently so
far) for posting this statement.  I'd just like to say that I agree with
you and that people should think about their questions a little before
posting them to this group.


*********************************************************************Stephen R. Lasky, Ph.D.
Roger Williams Medical Center/Brown University
Phone: 401-456-6572       Fax: 401-456-6569       e-mail: Stephen_Lasky at
"To me at least, 'Yuck' doesn't capture the full essence of death by
neurotoxin."   -Dick Dunn

More information about the Methods mailing list