'Good' Buffer with pKa of 5.3-5.4?

mamber mamber at synapse.bms.com
Mon Nov 7 18:10:21 EST 1994


I need a buffer system capable of holding the pH (ideally) between 5.35
and 5.4.  The pKa of MES (the 'Good' biological buffer with the lowest pH range
as listed in the Sigma catalog) is 6.1, with a working range that doesn't hold
well below 5.5 (as per my experiments).  I would be grateful to anyone that can
recommend an appropriate buffer for my needs.  Thanks, SWM

mamber at synapse.bms.com



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