plasmid curing

Takashi Hashimoto hasimoto at bs.aist-nara.ac.jp
Tue Nov 15 00:49:27 EST 1994


A friend of mine is dealing with a thermophilic bacterium that assimilates sulfur and contains one cryptic plasmid.  She wants to study whether the sulfur-assimilating ability is encoded on the main genome or in the plasmid and is trying to remove the plasmid from the bacterium.  She does not have any information on the genes on the plasmid (e.g. antibiotic resistance).  Does anybody know an efficient way for curing?  Thank you for your help.

Takashi Hashimoto
NAIST, Nara, Japan



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