We have used the anti-Taq antibody to solve the problem of doing a hot start in a capillary tube in a fast thermocycler. It seems to work in our hands at least. Joe -- Joseph Carnwath carnwath at tzv.fal.de Inst. fuer Tierzucht und Tierverhalten 31535 Neustadt Tel: (5043) 871-134 Germany Fax: (5034) 871-143