program for Motif identification?
Brian Foley
brianf at med.uvm.edu
Fri Sep 16 14:40:18 EST 1994
Daniel S. Chen (dschen at corona.hsc.usc.edu) wrote:
: Hi. I'm trying to analyze/characterize a protein and I am looking for
: a way to
: search for motifs. Specifically, I'm interested in a program that will
: Dan
The Protein Domain database PRODOM is now accessible on the Web at:
<a href= http://www.sanger.ac.uk/~esr/prodom.html >URL</a>
ProDom is a collection of protein domain families that have been generated
automatically from Swissprot by Blastp and the Domainer algorithm (See
Sonnhammer ELL & Kahn D (1994) Protein Science 3:482-492).
The ProDom WWW server allows you to query ProDom by keywords, Blast,
or directly with Swiss-prot acronyms. It also makes it very easy to
retrieve and display the families.
The main new feature of ProDom (apart from being updated to Swiss-prot 28)
is that it now graphically displays the domain organization of Swiss-prot
sequences according to ProDom. Also the algorithm has been improved to
cause less fragmentation of the sequences.
_______________
Erik Sonnhammer
Sanger Centre
Cambridge UK
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