DNA-binding protein

[WANZ at QUCDN.QueensU.CA]

Does anybody know a model of drug-induced protein phosphorylation
leading to DNA binding?  That is, cytosolic or nuclear protein
is phosphorylated upon drug treatment and binds DNA as a result.
What is your experience of testing the possibilities?  Is de novo
DNA-binding protein synthesis upon drug treatment more common than
protein modification?
Direct e-mail to my account is greatly appreciated.  Thank you.
Zhiwei Wang