EtBr carcinogenicity

Kenneth Howe howe at biology.UCSC.EDU
Thu Apr 27 14:56:13 EST 1995


"Vasos-Peter John Panagiotopoulos II, Columbia'81+, Bioengineer-Financier, NYC
BachMozart ReaganQuayleGramm EvrytanoKastorian; Cit:Mrquis WhWho Financ&Indus
aka 0003536867 at mcimail.com , 76530.1430 at compuserve.com (business ids)
 wrote:
If EtBr didn't attach to DNA it wouldn't be carcinogenic,
but then it wouldn't be useful as a marker.


If that's true, then does it also stand to reason that DNA-binding
proteins are carcinognic?  Magnesium?

Intercalation may often be correlated with carcinogenicity, but shouldn't
be used to define a chemical intercalator as a carcinogen without
independent proof.

ken



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