Galactosamine-induced liver injury: lethal dose?

insermet at univ-rennes1.fr insermet at univ-rennes1.fr
Fri Dec 8 04:24:02 EST 1995


Hi there.

I know that 20mg/100g is the minimal dose of D-Galactosamine to be
injected to induce acute liver injury on rats.

I would like to know if there is a lethal dose, and if there is a 
relation between dose and liver recovery time.

Are there examples of long-lasting injuries? At what dose?

Thanks a lot.

Olivier




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