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Antisense strand of DNA

Francisco G da Nobrega ib - bio 7588 fgdnobre at usp.br
Fri Dec 22 12:14:52 EST 1995

Dear Dr. Lasky:

I found your comments really precious. Maybe it is high time that some=20
sort of strict convention is negotiated between molecular geneticists=20
because every textbook writer apparently feels entitled to devise its own=
"intuitive"or "logical" rules. One can marvel at the multitude of=20
conventions just by reading the comments by Tanaka & Macer (TIG=20
10:417,94) and Coddington or Sam (TIG 11:124,95). You learn that Lewin=20
(Genes V) calls the 5'->3' strand "sense" while the template strand is=20
now the antisense or noncoding.
Maybe a teleconference held between the big textbook writers=20
(Alberts,Darnell,Suzuki,Zubay, Mays,etc. etc) with the participation of=20
some classical geneticists could settle the matter at the beginning of=20
the postgenome era (Science, 20 Oct 95)...
Happy Hollidays!


F.G. Nobrega
Universidade de S=E3o Paulo
Biologia - IBUSP
C.P.  11461
05422-970   S=E3o Paulo  -  SP  - Brasil
Voice: (011) 818-7588   Fax: (011) 818-7553    E-mail:  fgdnobre at usp.br

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