APOPTOSIS ASSAYS

Shahram Mori smori at nmsu.edu
Fri Jan 6 18:07:52 EST 1995


SHO1 (sho1 at aol.com) wrote:
: Apoptosis is reported to be detectable by a number of assays, most of
: which revolve around fragmented DNA. 

: What are the best assays for apoptosis?

: Are all assays equally reliable, or equally sensitive?

: Any experience with UNreliable assays? (We found the APOtag to be
: suboptimal.)
: Stuart Horowitz
: CardioPulmonary Research Institute
: Email: sho1 at aol.com
: Ph: 516-663-3917 Fax: 516-663-8874

I think Electromicroscopical assays are the best way to go. As a couple of
German scientists showed Apoptosis doesn't necessarily require DNA
fragmentation.

memb blebbing.
nucleus condensation.

 --
Shahram Mori					   _/\_
Program in Molecular Biology			  _\  /_
Dept. of chemistry and Biochemistry Box 3C	  \_  _/
NMSU  Las Cruces NM				    ||
88003





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