Smooth muscle cell-specific housekeeping genes?
bltihi at uta.fi
Tue Jan 24 02:12:04 EST 1995
Chung-Ming Hsieh (Hsieh at cvlab.harvard.edu) wrote:
: I am wondering if one can find a smooth muscle cell-specific housekeeping
: gene and use it as a probe to control the smooth muscle cell RNA proportion
: in various tissues. I have looked into alpha-smooth muscle actin and it is
: not expressed at the same level in the digestive system and the vascular ...
Alpha-SMC actin in NB:s is not SMC-specific, since probably all the
actins cross-hybridize due to highly similar sequences, and all cell-types
express some kind of actin (at least I think so).
It would really be very interesting to hear about a gene that is expressed
only in smooth muscle cells in quantities sufficient for NB detection.
from the Univ. of Tampere, Finland
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