mouse vs human

bcdlee at hkpucc.polyu.edu.hk bcdlee at hkpucc.polyu.edu.hk
Tue Mar 14 03:42:48 EST 1995


In article <9503081344.AA00390 at compbio2.med.wayne.edu>, jeff at COMPBIO2.MED.WAYNE.EDU (Jeff Kramer) writes:
> Good morning all.
> 
> 	I'm looking for a sequence, probably a coding region that codes for a 
> highly conserved a highly conserved protein, that is very close to identical
> between mouse and human.  Basically, I hope to design two primers that will
> work in both mouse and in human genomic DNA, so anything similar enough to give
> a few stretchs of 20 or so nucleotides that are the same, so that I have a 
> chance of designing primers that are compatible with one another would be
> ideal.  Does such a thing exist, or am I hoping too much?  I have primer sets
> for mouse and human actin which are different.  I would think my best chance
> for finding primers that would work on with both species would be in a highly
> conserved structural gene or some such, but I just don't know.  Thanks in 
> advance for your input...
> 
> 							-Jeff
Try the core histone genes. They are probably your best bet.

Daniel Lee
Hong Kong Polytechnic University



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