SV40

Daniel, Phil danielp at whio.lincoln.ac.nz
Wed Mar 15 16:34:44 EST 1995


In article <3k10km$1jb at mserv1.dl.ac.uk> "HANELT" <sabine.hanelt at medizin.uni-ulm.de> writes:
>From: "HANELT" <sabine.hanelt at medizin.uni-ulm.de>
>Subject: SV40
>Date: 13 Mar 1995 08:44:06 -0000

>Hey netters,
>I'm working with the human fibroblast cell line MRC5CV1. Does anyone know
>if there is a risk for human working with SV40 transformed cell lines?
>If there is any literature about it, please let me know.
>Thank's for your help
>Sabine

>Sabine.Hanelt at medizin.uni-ulm.de

SV40 transformed cell lines are usually handled in biohazard hoods to reduce 
risk of exposure. Humans can apparently pick up this virus, but I don't know 
of any proven disease associations. 
An article in New Scientist (21 may 1994, page 4) mentions SV40 as a 
contaminant in early polio vaccines (1954-1963) administered to millions of 
people. The article goes on to discuss how a mystery virus found in 
mesothelioma cells (asbestosis related lung cancer) appears to be SV40. I 
would be interested to learn of any further work in this area, or other 
disease associations of SV40.

>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
Philip Daniel                |  danielp at lincoln.ac.nz 
Animal & Vet. Sciences Group |  address valid until april 27 1995
Lincoln University           |
New Zealand                  |
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