An enzyme degrading dsDNA but not ssDNA

Mr. J. Sasse jsasse at
Sun Mar 19 09:11:58 EST 1995

Hello Netters,
Does anybody know of an enzyme which will degrade dsDNA randomly
but not ssDNA. Could I use DNase I with a specialised buffer allowing digest dsDNA?
Thanks a lot for all you help.

Jurgen Sasse
email: js1 at

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