Temp. Gradient Gel Electrophoresis/GC clamps

MARLENE SNYDER msnyder at ace.acadiau.ca
Mon Mar 20 15:57:24 EST 1995


I am trying to figure out just how TGGE works, and why the GC clamp 
facilitates TGGE detection of single base substitutions within a fragment.  It 
seems to me the clamp would prevent melting, but melting is what is desired, 
isn't it?  What am I missing here...

Thanks, 
Marty Snyder



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