formaldehyde pH

Harry Yim hyim at SOL.CHMC.ORG
Thu Mar 23 16:28:12 EST 1995


I understand the for RNA formaldehyde gels, the pH of the formaldehyde should be above 4 or it is no good.  All the bottles in the department turned out to have a pH between 3.3 and 3.6 so I ordered a new bottle of 37% formaldehyde.  Today it arrived and it turns out to have a pH of 2.33!  The technical service rep was of no use so I hope someone out there can help me.  Should I not worry about the pH or can I de-ionize it to get rid of the formic acid (I presume that this is what is loering the pH)?  Thanks for any help.

Harry Yim
Children's Hospital and Medical Center
Department of Infectious Diseases
4800 Sand Point Way NE
Seattle, WA 98105
hyim at

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