Q:Taq and deletions

[Piotr Kozlowski]

Dear Netters,
Does anyone have any suggestion on principles of generation of large 
deletions (~500 bp) in amplificated DNA caused by the activity of Taq 
polymerase during PCR?
Thank you in advance for any suggestion.



Piotr Kozlowski
Institute of Biochemistry
Warsaw University
ul. Zwirki i Wigury 93
02 089 Warsaw, POLAND
Tel./Fax (+48 22) 23 20 46
E-mail: koziol at asp.biogeo.uw.edu.pl