In article <475mej$r6u at sifon.cc.mcgill.ca> Petros, BKXO at musicb.mcgill.ca writes:
>I would like to differentiate by gel electrophoresis between DNA
>fragments differing in size by as little as a few base pairs. The size of
>the DNA fragments are between 500-900bp and some differ by as little
>>Can anyone suggest a high resolution mini-gel system that might
>accomplish separation of DNA fragments differing in size by as little
>BKXO at musicb.mcgill.ca>
I believe the Hoefer Tall Mighty Small rig is capable of single base
resolution, and there is a paper in which it was used to sequence DNA.
Call them for details. If you need it, I could give you the citation.
dkim at nmsu.edu