In article <494ard$ovt at gnu.mat.uc.pt>, scurado at gemini.ci.uc.pt (Silvia
> Anyone who, by any chance, is working (or knows someone working) on
> molecular genetics (PCR) as an approach for the evaluation of minimal
> disease in leukaemia?...
>> If so, would you kindly send me "the tip"?!
This technique is being used to detect residual bcr-abl expressing chronic
myelogeous leukemia cells. Do a lit search on bcr-abl or CML and pcr and
you'll find the refs. Here are some places to start if you don't have the
ability to do the lit searches:
Lion, T et al, Leukemia, 9:1353-1360, 1995
Van Rhee, F et al, British Journal of Haematology 90:225-228 1995
Devaraj, P. E et al, British Journal of Haematology 89:349-355, 1995
Cross, Ncp et al, Leukemia, 8:186-189, 1994
Pichert, G et al, Leuk Lymphoma, 10:1-8, 1993
Hope that helps
Stephen R. Lasky Ph.D.
Section of Experimental Therapeutics
Roger Williams Medical Center
Providence, RI 02908
Phone: 401-456-5672 Fax: 401-456-6569
e:mail: Stephen_Lasky at brown.edu