Stability of recom. antibodies?

Peter pemanuel at
Wed Oct 4 10:10:41 EST 1995

Has anyone noticed that recombiant Fab antibodies are more or less atble
than whole immunoglobulin?
I have produced soluble Fabs which are very active during the first use
but following a freeze thaw they lose much of their activity.  What can be
done to avoid this.

Peter Emanuel Ph.D.
University of Maryland School of Medicine
4-027 Bressler Research Building
655 West Baltimore Street
Baltimore, MD 21201

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