In article <sargueil-0510951008420001 at zebulon.cgm.cnrs-gif.fr>, sargueil at smigiris.cgm.cnrs-gif.fr (bruno Sargueil) wrote: >I'm having trouble to use glyoxal to denature RNA and run them on agarose gels. For us, the major problem with glyoxal has been incomplete de-ionization. If its pH is very acidic, don't use it.