Ganciclovir Cell Selection

Bob Harrison RBHR at BPHVAX.BIOPHYSICS.ROCHESTER.EDU
Tue Sep 12 10:58:25 EST 1995


I have been trying to use HSV thymidine kinase and ganciclovir to 
select non-embryonal cultured mammalian cells.  Cells expressing this 
enzyme seem to vary in their sensitivity to ganciclovir, including 
being insensitive at times.  Has anyone else had a similar experience 
or is there an explanation??

Bob Harrison



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