mg+2/ca+2 atpase

Mr Vid Mohan-Ram k9mhc at
Tue Apr 16 07:40:54 EST 1996


ok...divalent cations,eg mg+2 and ca+2, form ionic associations
with questions are:

1) can atp bind to its binding pocket in the absence of these cations?
2) if it can bind does catalytic activity remain?
3) is a mg+2 ion required in the base of the binding pocket in
   order for hydrolysis?

 this is with respect to myosin heavy chain atpases so any relevent
help there would be appreciated.....



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