mg+2/ca+2 atpase

Mr Vid Mohan-Ram k9mhc at .rfhsm.ac.uk
Tue Apr 16 07:40:54 EST 1996


hi

ok...divalent cations,eg mg+2 and ca+2, form ionic associations
with atp...now...the questions are:

1) can atp bind to its binding pocket in the absence of these cations?
2) if it can bind does catalytic activity remain?
3) is a mg+2 ion required in the base of the binding pocket in
   order for hydrolysis?

 this is with respect to myosin heavy chain atpases so any relevent
help there would be appreciated.....

thanks

vid




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