Specific MAPK-K inhibitor
Alan K. Howe
alanhowe at merle.acns.nwu.edu
Fri Feb 2 19:16:14 EST 1996
There's an organic compound that was discovered by a group at
Parke-Davis that specifically inhibits MEK (MAP kinase kinase)
activity. It was described in PNAS, sometime in the middle or
end of '95. My questions are two fold:
1.) Has anybody used this compound, and if so, what do you think?
2.) How did you get it? Can you order some from Parke-Davis, or
did you have to write to the authors of the PNAS paper and wait a
year for a response?
Any practical information on this compound would be enormously
appreciated.
--
Alan K. Howe
Northwestern University, Chicago, IL. USA
alanhowe at merle.acns.nwu.edu
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