want comments on phosphorimagers: Molec.Dynamics vs BioRad
tvasicek at watson.princeton.edu
Thu Feb 8 15:57:11 EST 1996
In article <4f8si0$3ge at elaine28.Stanford.EDU>, blakely at leland.Stanford.EDU
(Bruce Thomas Blakely) wrote:
> Our department is looking at phosphorimagers and I would be interested
> in opinions on why we should or should not buy a particular brand.
I recently posted a note about our frustration with our department's old
Molecular Dynamics system. I mentioned that I liked a BioRad demo that I
had seen, but I admit that I have no idea what sort of record BioRad has.
The new MD Storm system sounds great and it fixes all of the problems we
have with the old system. I have used MD phosphorimagers and
densitometers for >10 years and have found MD to be a good company.
In response to my posting, I recieved the following message from the MD
guy. I also got a phone call from the company and a visit from a sales
rep. I hope folks don't mind my forwarding a note that originated at a
company -- it most concisely answers the questions at hand.
In light of Dr. Vasicek's comments I must explain that the original
PhosphorImager systems introduced by Molecular Dynamics in 1989 had
20MHz Compaq 386 systems hardwired into the instrument. They could
display images using 8 levels of gray or 16 colors. By today's
standard they were infuriatingly slow, but these computers were among
the best of their day. The ImageQuant software for instrument control
and image analysis was available for the built-in PC systems only.
A while back Molecular Dynamics made all of our PhosphorImager,
densitometer, and FluorImager systems SCSI peripheral devices, so now
our customers can use the fastest Macintosh and PC systems available
rather than a hardwired internal system. The ImageQuant software has
been completely re-written to take advantage of the 32-bit Windows NT
operating system and Macintosh. The customer interface is menu and
pushbutton-driven, like popular image processing packages such as
Our latest storage phosphor autoradiography system, introduced last
year, is called Storm. It offers 50Ê resolution scanning and reads
fluorescent and chemifluorescent gels and blots as well as
radioisotope-generated images so you can use it for both radioactive
and nonradioactive imaging and analysis.
There are more than 1,000 Molecular Dynamics PhosphorImager systems
installed in life science research laboratories worldwide. Molecular
Dynamics PhosphorImager systems are commonly cited in papers published in
Science, Nature, Nature Genetics, Nature Medicine, Biochemistry, Cell and
Thomas J. Vasicek, Ph.D. tvasicek at watson.princeton.edu
Department of Molecular Biology FAX: 609/258-3345
Princeton University Phone: 609/258-2899
Princeton, New Jersey 08544
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