Do DNA DE-methylases exist?
Brad_Nicholson at hlthsci.med.utah.edu
Tue Feb 13 16:56:35 EST 1996
In article <4fm9m2$ioc at lyra.csx.cam.ac.uk>, Peter Wang
<plw at mrc-lmb.cam.ac.uk> wrote:
>Someone was asking me about restriction endonucleases and methylases,
>and had the interesting question of whether or not there are enzymes
>that de-methylate DNA.
As far as bacteria go, there are no specific DNA de-methylases known.
There is a repair pathway that can remove methyl groups (fuzzy memory here,
it was first described in Science a few years back, let me know if you
really wan't to know.) I believe that there are de-methylases in
eucaryotes and this may be involved in development. I imagine others on
this group could better describe this activity.
Brad Nicholson |"If it worked the first time,
Department of Pathology | it wouldn't be research."
University of Utah | ...Brad Nicholson
Salt Lake City, UT 84132 | My opinions are solely my own.
Brad_Nicholson at hlthsci.med.utah.edu |
or: (801)-581-4365 | iligitimi non corborundrum
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