Do DNA DE-methylases exist?

Joao Vasconcelos Costa jcosta at pen.gulbenkian.pt
Wed Feb 14 02:32:18 EST 1996


Brad Nicholson wrote:
(...)
> As far as bacteria go, there are no specific DNA de-methylases known.
> There is a repair pathway that can remove methyl groups (fuzzy memory here,
> it was first described in Science a few years back, let me know if you
> really wan't to know.)  I believe that there are de-methylases in
> eucaryotes and this may be involved in development.  I imagine others on
> this group could better describe this activity.
> 

As far as I know, there are no eukaryotic demethylases. Am I wrong?

-- 
*****   JOAO VASCONCELOS COSTA, MD, PhD
*****   Instituto Gulbenkian de Ciencia - Oeiras, Portugal
*****   mailto:jcosta at pen.gulbenkian.pt
*****   http://www.pen.gulbenkian.pt/v2/jvc.html



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