Do DNA DE-methylases exist?
qshang at u.washington.edu
Wed Feb 14 19:14:06 EST 1996
On Wed, 14 Feb 1996, Joao Vasconcelos Costa wrote:
> As far as I know, there are no eukaryotic demethylases. Am I wrong?
There are O6-methylguanine transferases which is a suicide enzyme that
removes the methyl group on guanines and becomes inactivated
permanently. I don't think it is sequence specific though. There are
also other methyl transferases; maybe some of them have sequence
specificity, but I don't know.
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