Retroviruses and viral vectors

Matthew Dubeck RRRP87C at
Thu Jan 4 22:39:03 EST 1996

I have two questions which I hope somebody can help me answer.

1.  Is there anyway to remove the reverse transcriptase from a retrovirus 
while maintaining the viability of the virus?  By this I mean, without 
destroying the virus.

2.  How are viral vectors created?  If I have a piece of DNA (or RNA in 
the case of retroviruses) what is standard procedure for getting it into 
the viral genome?

Thank you for any help you can offer.

Matthew Dubeck
RRRP87C at

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