PCR fidelity

Warren Gallin wgallin at gpu.srv.ualberta.ca
Thu Jan 4 17:09:35 EST 1996

In Article <4ch8b1$6cc at hpngsv01.mgh.harvard.edu>, Micheal FitzGerald
<fitzgerald at helix.mgh.harvard.edu> wrote:
>If an error is incorporated in the first amplification cycle
>it will comprimise 1/4 of the final product at that position.

And less if more than one template molecule is there in the first place
(which is far and away usually the case.

Warren Gallin,
Department of Biological Sciences, University of Alberta
wgallin at gpu.srv.ualberta.ca

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