Antisense and sensibilities
Stephen R. Lasky
Stephen_Lasky at brown.edu
Thu Jan 11 08:44:24 EST 1996
In article <4d11p1$41v at epx.cis.umn.edu>, horton at biosci.cbs.umn.edu (Robert
Horton) wrote:
> Stephen R. Lasky (Stephen_Lasky at brown.edu) wrote:
>
> : Why not define the strands based on the action that is taken on them: the
> : transcribed strand (T-Strand) (for the anti-parallel complementary strand
> : to the mRNA), and the non-transcirbed stand (N-Strand) for the strand with
> : the same sequence as the mRNA? The name of the gene that is transcribed
> : can be added if it has not already been defined (as suggested by Dr.
> : Moldwin). mRNA should be mRNA or sense-RNA, and anti-Sense RNA should be
> : the anti-parallel complement to the message. I don't see any ambiguity in
> : this system.
>
> (Bob emerges from phone booth wearing Devil's Advocate costume):
> Except that "T" and "N" are both used to denote nucleotides!
>
Bob: Hadn't really thought of that, but if you use T-strand and N-strand,
you shouldn't get them confused with NTP or TTP (or any other
nucleoside). ???
SRLasky
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Stephen R. Lasky Ph.D. Brown U/Roger Williams Medical Center, Providence, RI.
Phone: 401-456-5672 Fax: 401-456-6569 e:mail: Stephen_Lasky at brown.edu
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America may be unique in being a country which has leapt from barbarism to decadence without touching civilization. John O'Hara.
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