In article <4p4ib1$bpi at mserv1.dl.ac.uk>, RMCMAH93 at IRLEARN.UCD.IE says: > > >I have been exposing oligos to multiple freeze thaws. They are also >being stored in a frost free freezer. Is this likely to break the >biotin:oligo bond? >Thanks in adavance, >Ruth. No. They are chemically very stable. make sure it is sterile though. John Fox