RNA secondary structure predictions - G-U pairing

[Emmanuel Skoufos]

On Tue, 25 Jun 1996, reset wrote:

> Hello all!
> 
> I have been using RNAdraw from Ole Maatsura's lab to predict secondary
> structures of viral sequences. The program allows the user to allow or
> disallow G-U pairing in its calculations of structure and energy. I
> would like to know which scenario is closer to actual in vivo
> conditions. Thanks in advance!!

G-U pairing most likely exists _in vivo_.
A good starting point for RNA folding references is Mike Zuker's RNA Page:

<http://www.ibc.wustl.edu/~zuker/rna/>

There you will find many answers and pointers to RNA structure questions


> 
> Jose E. N. Gonzales
> The Immune Response Corporation
> Carlsbad, CA
> 
> 
> 

Emmanuel Skoufos, Ph.D.  
Yale University School of Medicine    
Department of Molecular Biophysics and Biochemistry
217 Bass Center P.O.Box 208114
266 Whitney Ave.
New Haven, CT 06510-8114
phone: (203) 432-6564 or (203) 432-6543
FAX: (203) 432-5175