Type I & II membrane proteins?

John H Richburg John_H_Richburg at Brown.edu
Fri Nov 8 13:14:35 EST 1996

I often see in the literature reference to a protein being a type I or
type II membrane protein. However, I am a bit confused about the
definition of these types (are there more than type I & II. I am almost
sure that the definition refers to the placement of the -COOH and NH2
terminius (extracellular vs intracellular). I would appreciate if aybody
has more insight into this issue and would be very grateful for a
reference source which defines these membrane protein types.

Thank you,

John Richburg
Dept. Pathology and Laboratory Medicine
Brown University

John_H_Richburg at brown.edu

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