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myelomas for heterologous protein expression?

Gregg B Wells wellsg at mail.med.upenn.edu
Thu Oct 10 13:52:30 EST 1996

Has anyone done much with the production of non-immunoglobulin proteins
from myeloma cell lines? Are protein expression vectors available with
immunoglobulin signal sequences or immunoglobulin promoters?  I think that
myeloma cell lines would be excellent producers for heterologous protein
expression, but I could find very little literature other than for
immunoglobulin-type proteins.

Thanks for insights on this topic.

Gregg Wells
Department of Pathology
University of Pennsylvania
Philadelphia, Pennsylvania
email:  wellsg at mail.med.upenn.edu

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