Haptoglobin
is a highly polymorphic protein. Genotyping
is usually done by isoelectric focusing. I would like to know,
if there is a * PCR based* method to demonstrate HP alleles.
It should be possible as the underlying DNA variations are known.
(The Genome Data Base -GDB- lists HP variants that are detected
by Southern blotting and HP probe hybridization )
Thank you very much for helpful hints!
Manfred Schuermann, M.D.
Institute of Human Genetics
University of Luebeck Medical School, Germany
e-mail msms at on-luebeck.de
phone +49 451 500 2620
fax +49 451 500 4187