Bis-tris-propane: temp. coeff. (dpKa/dT) ??

Achim Recktenwald achim at ibex.ca
Wed Sep 4 16:48:25 EST 1996


Hi all,

I am looking for the temperature coefficient(s) [dpKa/dT] of the
buffer-substance
'bis-tris-propane' = 1,3-bis[tris(hydroxymethyl)methylamino]propane 
for some enzyme kinetic experiments.  

According to the supplier (Sigma) it has the pKa-values:
pKa1=6.8 and pKa2=9.0 at T=25C.

Sigma doesn't know the dpKa/dT-value(s) either.
Can anybody help ?


Thanks,

Achim



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