D. Scott Snyder
dss10 at acpub.duke.edu
Wed Sep 25 10:53:06 EST 1996
Another possibility is that the protein, having evolved to work at higher
temperatures, may actually require such temperatures for stability.
Remember that the hydrophobic and H bonding forces holding the enzyme
together are entropy dependent (A similar phenomenon has been noted with other
proteins called "cold denaturation".).Its optimum pH for stability may also
play a role as many side groups have pKas that vary with temp.
Hope this helps.
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