Denaturing proteins for IP

[Louis Hom]

I need to IP my S35-labeled protein out of my cell lysates (there's an
interfering protein of similar molecular weight), but unfortunately my
antibody only binds the denatured form.  Any suggestions on how I might go
about this? 
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Lou Hom >K '93					
lhom at nature.berkeley.edu 	
http://www.ocf.berkeley.edu/~lhom