Small peptides transfering through PVDF membrane

Andrey S. Shaw shaw at immunology.wustl.edu
Sat Aug 2 22:25:30 EST 1997


Abolutely.  The peptide is going through.  If you ever try placing two
membranes back to back, you will see that a lot of even large proteins
will bo through.  That is because the membrane has a pore (which is
usually .2 or .45 microns).  Also the basis of protein binding to
membraens is based on the physical (hybrophobic) properties of the
protein and it is more likely that small peptides will not have enough
hydrophobicity to bind to the membrane.

andrey shaw



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