Human Ig gene-diversity

Troels Wind wind at biobase.dk
Tue Jul 22 09:32:16 EST 1997


Hi all,

I'm currently trying to collect some data on the HUMAN Ig-loci and now
I turn to you for some easy obtainable info.     ^^^^^

The problem is that I cant find any refs that states the accurate number
of various Ig gene-segments in humans, only those in mouse. So far I've
got the following:

#VH fragments: 51 (something tells me that the true number is 49...?)
#D fragments: ?
#JH fragments: ?
#VL(kappa) fragments: ?
#VL(lambda) fragments: 37
#JL(kappa) fragments: 5
#JL(lambda) fragments: ?

Evidently this is a very incomplete list, can you help me out?

Thanks in advance!

Troels Wind
Aarhus University
Denmark





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