Protein-protien interaction by cross-linking!

Dr. Alex Bogdanov abogdanov at helix.mgh.harvard.edu
Wed Jul 23 13:49:16 EST 1997


> I think you
>use paraformaldehyde. Try looking up medline with (para)formaldehyde >and
>homodimer or multimer.

It would be more reasonable to try bis-imidates or bis-sulfosuccinimide
esters. Both were in use for the purpose of protein cros-linking for at
least 15 years. Pierce Chem. Co is the source.



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